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Campo DC | Valor | Lengua/Idioma |
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dc.contributor.author | Roig, Francisco J. | - |
dc.contributor.author | Amaro Gonzalez, Carmen | - |
dc.contributor.author | Alcaine Otín, Alejandro | - |
dc.contributor.author | Carro, Jesús | - |
dc.date.accessioned | 2023-10-18T14:34:36Z | - |
dc.date.available | 2023-10-18T14:34:36Z | - |
dc.date.issued | 2023-08-09 | - |
dc.identifier.citation | Roig Molina FJ, Amaro González C, Alcaine Otín A and Carro Fernández J (2023) Vibrio vulnificus mutation rate: an in vitro approach. Front. Microbiol. 14:1223293. doi: 10.3389/fmicb.2023.1223293 | en_US |
dc.identifier.issn | 1664-302X | en_US |
dc.identifier.uri | https://repositorio.usj.es/handle/123456789/1004 | - |
dc.description.abstract | Vibrio vulnificus is a multi-host pathogenic species currently subdivided into five phylogenetic lineages (L) plus one pathovar with the ability to infect fish due to a transmissible virulence plasmid. This plasmid (or a fragment of it) has been transmitted between lineages within the species, contributing to the evolution of V. vulnificus. This study aimed to provide an experimental approximation to the V. vulnificusmutation rate by determining spontaneousmutation rates frombacterial cultures of representants of the dierent lineages by whole-genome sequencing. To this purpose, synonymous SNP dierences, i.e., spontaneous mutation not subjected to the evolutive forces, between initial and final culture after serial growth were evaluated and used for mutation rate calculation | en_US |
dc.format.extent | 9 p. | en_US |
dc.format.mimetype | application/pdf | en_US |
dc.language.iso | eng | en_US |
dc.publisher | FRONTIERS | en_US |
dc.relation | This study was partially funded by Departamento de Ciencia, Universidad y Sociedad del Conocimiento, from the Gobierno de Aragon (Spain) (Research Group T71_23D). This study also forms part of the ThinkInAzul program and was supported by grant THINKINAZUL/2021/027 from MCIN (Ministerio de Ciencia e Innovacion de Espana) with funding from European Union NextGeneration EU (PRTR-C17.I1) and GV (Generalitat Valenciana). The study was also supported by grants PID2020-120619RB-I00 funded by MCIN/AEI/10.13039/501100011033 and AICO/2020/076 funded by GV. This study was also supported by Universidad San Jorge (internal call for Open Access publication grants 2022-2023). | en_US |
dc.rights | Atribución 4.0 Internacional | * |
dc.rights.uri | http://creativecommons.org/licenses/by/4.0/ | * |
dc.subject | Mutation rate | en_US |
dc.subject | Number of generations | en_US |
dc.subject | Vibrio vulnificus | en_US |
dc.subject | Lineages | en_US |
dc.subject | Evolution | en_US |
dc.title | Vibrio vulnificus mutation rate: an in vitro approach | en_US |
dc.type | info:eu-repo/semantics/article | en_US |
dc.identifier.doi | https://doi.org/10.3389/fmicb.2023.1223293 | en_US |
dc.rights.accessrights | info:eu-repo/semantics/openAccess | en_US |
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Vibrio vulnificus mutation rate.pdf | 166,8 kB | Adobe PDF | Visualizar/Abrir |
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