Please use this identifier to cite or link to this item: https://repositorio.usj.es/handle/123456789/374

Full metadata record
DC FieldValueLanguage
dc.contributor.authorÁlvarez, Alejandro González-
dc.contributor.authorGómez Barrera, Manuel-
dc.contributor.authorBlasco, Joaquín Borrás-
dc.contributor.authorSerret, Emilio José Giner-
dc.date.accessioned2020-04-17T08:08:51Z-
dc.date.available2020-04-17T08:08:51Z-
dc.date.issued2014-08-12-
dc.identifier.citationÁlvarez, A. G., Barrera, M. G., Blasco, J. B., & Serret, E. J. G. (2014). Adalimumab and etanercept in the treatment of rheumatoid arthritis and spondyloarthropathies: Budget impact model of dose reduction. Journal of Pharmacy and Nutrition Sciences, 4(3), 170-176. doi:10.6000/1927-5951.2014.04.03.1es_ES
dc.identifier.issn1927-5951/14es_ES
dc.identifier.urihttps://repositorio.usj.es/handle/123456789/374-
dc.description.abstractAbstract: Objective: To assess the financial impact of spacing out the administration intervals of adalimumab (ADA) and etanercept (ETN) in the treatment of rheumatoid arthritis (RA) and spondyloarthropathies (SAP) in our work setting. Materials and method: A budget impact model (BIM) was developed to estimate the financial impact of spacing out the usual administration intervals of ADA 40 mg every 2 weeks and ETN 50 mg weekly (scenario A) to ADA 40 mg every 3 weeks and ETN 50 mg every 2 weeks (scenario B), according to the guidelines and recommendations applied to these studies, specifying the target population, the study perspective, the time frame, and analysing the robustness of the study with a threshold univariate sensitivity analysis. Results: A total of 71 patients were included in the study. The application of a BIM showed annual savings for ADA and ETN of €19,784 and €38,271, respectively. The net cost, that is, the savings this entailed for the time frame considered (2 years), amounted to 116,110. The sensitivity analysis performed shows that the BIM estimated for the study period was very robust, as the net result in the different scenarios varied very little, remaining negative in the new scenarios. Conclusions: The BIM developed in the study shows the importance of the role of healthcare professionals in the context of sustainability of the healthcare system, where the model could generate large annual net savings for the different regional healthcare systems.es_ES
dc.format.mimetypeapplication/pdfes_ES
dc.language.isoenges_ES
dc.publisherSetpublisheres_ES
dc.rightsAttribution-NonCommercial-NoDerivatives 4.0 Internacional*
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/4.0/*
dc.subjectArtritis reumatoidees_ES
dc.subjectEspondiloartropatíases_ES
dc.subjectAdalimumabes_ES
dc.subjectEtanerceptes_ES
dc.subjectTumor inhibidores alfa del factor de necrosises_ES
dc.titleAdalimumab and Etanercept in the Treatment of Rheumatoid Arthritis and Spondyloarthropathies: Budget Impact Model of Dose Reductiones_ES
dc.typeinfo:eu-repo/semantics/articlees_ES
dc.subject.unescoFarmacologíaes_ES
dc.relation.publisherversionhttps://setpublisher.com/downloads/jpansv4n3a1-alvarez/es_ES
dc.identifier.publicationfirstpage170es_ES
dc.identifier.publicationlastpage176es_ES
dc.identifier.doihttp://dx.doi.org/10.6000/1927-5951.2014.04.03.1es_ES
dc.rights.accessrightsinfo:eu-repo/semantics/openAccesses_ES
Appears in Collections:Artículos de revistas

Files in This Item:
File Description SizeFormat 
Adalimumab and Etanercept in the Treatment of Rheumatoid.pdf637,81 kBAdobe PDFThumbnail
View/Open


This item is licensed under a Creative Commons License Creative Commons